Work Experience
Dec, 2000-present，Chongqing University, China，Professor
Sep, 1996-Sep, 1997,Visiting Scholar, University of Bath,UK
Jul, 1991-Sep, 1996, Associate Professor and Lecturer, Southwestern Agricultural University
Jul, 1985-Aug, 1988，Engineer, Nanchong Forestry Research Institute
Education:
Oct, 1997 – Nov, 2000 University of Bath, Doctor of Philosophy in Biochemistry
Sep, 1988 – Jul, 1991 Southwestern Agricultural University, Master of Science in Crop Genetics
Sep, 1981 – Jul, 1985 Si Chuan Agricultural University, Bachelor of Science in Forestry
Research interests
Molecular mechanisms of conidiation, pathogenicity, stress tolerance in entomopathogenic fungi. Molecular mechanism of insect immunicty against entomopathogenic fungi; Development of fungal pesticides.
Courses
Course: Fermentation engineering
Academic position
Vice-editor of Journal of Chinese Biotechnology
Major achievement
Pulications
【1】Zhang E。 , Cao Y., Xia Y。 Ethanol dehydrogenase I contributes to growth and sporulation under low oxygen condition via detoxification of
acetaldehyde in Metarhiziumacridum，Front. Microbiol.2018，9:1932
【2】Li G., Fan A., Peng G., Keyhani NO., Xin J., Cao Y. Xia Y，A bifunctional catalase-peroxidase, MakatG1, contributes to virulence of
Metarhizium acridum by overcoming oxidative stress on the host insect cuticle，Environ Microbiol，2017,19(10): 4365–4378
【3】Zhang W, Chen J, Keyhani NO, Jin K, Wei Q, Xia Y，Central Nervous System Responses of the Oriental migratory, Locusta migratoria manilensis,
to Fungal Infection.Sci Rep.2017 ;7(1):1034
【4】Zhang J,Jin K, Xia Y,Contributions of β-tubulin to cellular morphology, sporulation and virulence in the insect-fungal pathogen, Fungal Genet
Biol.2017, 103:16-24
【5】Hong M.，Peng G., Keyhani NO, Xia Y.Application of the entomogenous fungus, Metarhizium anisopliae, for leafroller (Cnaphalocrocis medinalis)
control and its effect on rice phyllosphere microbial diversity，Appl Microbiol Biotechnol，2017,101:6793–6807
【6】Hu J, Xia Y.Increased virulence in the locust-specific fungal pathogen Metarhizium acridum expressing dsRNAs targeting the host F1 F0 -ATPase
subunit genes.Pest Manag Sci，2018 May 23. doi: 10.1002/ps.5085
【7】Hu J, Xia Y.F1-ATP synthase α subunit: a potential target for RNAi-mediated pest management of Locusta migratoria manilensis.Pest Manag
Sci2016, 72:1433- 1439
【8】 Wang ZL, Jin K, Xia YX. Transcriptional analysis of the conidiation pattern shift of the entomopathogenic fungus Metarhizium acridum in
response to different nutrients. BMC Genomics. 2016, 17: 586.
【9】 Zhang W., Wanchoo A., Ortiz-Urquiza., Yuxian Xia, and Nemat O. Keyhani. Tissue, developmental, and caste-specific expression of
odorant binding proteins in a eusocial insect, the red imported fire ant, Solenopsis invicta. Scientific Reports, 2016, 6.
【10】 Jin K, Peng GX, Liu YC, Xia YX. The acid trehalase, ATM1, contributes to the in vivo growth and virulence of the entomopathogenic fungus,
Metarhizium acridum. Fungal Genetics and Biology. 2015, 77: 61-67.
【11】 Ma QS, Jin K, Peng GX, Xia YX. An ENA ATPase, MaENA1, of Metarhizium acridum influences the Nai+-, thermo- and UV-tolerances of conidia and
is involved in multiple mechanisms of stress tolerance. Fungal Genetics and Biology.2015, 83: 68-77.
【12】 Peng GX, Jin K, Liu YC, Xia YX. Enhancing the utilization of host trehalose by fungal trehalase improves the virulence of fungal
insecticide. Applied Microbiology and Biotechnology. 2015, 99(20):8611-8618.
【13】 Zhang W, Chen J, Keyhani NO, Zhang Z, Li S, Xia Y. Comparative transcriptomic analysis of immune responses of the migratory locust, Locusta
migratoria, to challenge by the fungal insect pathogen, Metarhizium acridum. BMC genomics 2015, 16: 867-
【14】 Ming Y, Wei QL, Jin K, Xia YX. MaSnf1, a sucrose non-fermenting protein kinase gene, is involved in carbon source utilization, stress
tolerance and virulence in Metarhizium acridum. Applied Microbiology and Biotechnology. 2014, 98: 10153-10164.
【15】 Cao Y., Du M., Luo S., Xia Y. Calcineurin modulates growth, stress tolerance, and virulence in Metarhizium acridum and its regulatory
network. Applied Microbiology and Biotechnology. 2014, 98: 8253-8265
【16】 Zhang W., Xia Y. ER type I signal peptidase subunit (LmSPC1) is essential for the survival of Locusta migratoria manilensis and
affects moulting, feeding, reproduction and embryonic development. Insect molecular biology, 2014, 23(3): 269-285.
【17】 Jin K, Han LR, and Xia YX. MaMk1, a FUS3/KSS1-type mitogen-activated protein kinase gene, is required for appressorium formation, and
insect cuticle penetration of the entomopathogenic fungus Metarhizium acridum. Journal of Invertebrate Pathology. 2014, 115(1): 68-75.
【18】 Luo S., He M, Cao Y, Xia Y. The tetraspanin gene MaPls1 contributes to virulence by affecting germination, appressorial function and
enzymes for cuticle-degradation in the entomopathogenic fungus, Metarhizium acridium. Environmental Microbiology 2013, 15 (11): 2966-2979.
【19】 Jin K, Ming Y, and Xia YX. MaHog1, a Hog1-type mitogen-activated protein kinase gene, contributes to stress tolerance and virulence of the
entomopathogenic fungus Metarhizium acridum. Microbiology-SGM. 2012, 158(12): 2987-2996.
[【20】 Cao Y., Zhu X., Jiao R., Xia Y. The Magas1 gene is involved in pathogenesis by affecting penetration in Metarhizium acridum. Journal of
Microbio1ogy and Biotechnology. 2012, 22: 889–893 .
【21】 Cao Y., Jiao R., Xia Y. A strong promoter, PMagpd, provides a tool for high gene expression in entomopathogenic fungus, Metarhizium acridum.
Biotechnology letters, 2012, 34: 557 – 562.
【22】 Gao Q, Jin K, Ying S, Zhang Y, Xiao G, Shang Y, Duan Z, Hu X, Xie X, Zhou G, Peng G, Luo Z, Huang W, Wang B, Fang W, Wang S, Zhong Y, Ma L,
St. Leger RJ, Zhao G, Pei Y, Feng M*, Xia Y*, Wang C* Genome Sequencing and Comparative Transcriptomics of the Model Entomopathogenic Fungi
Metarhizium anisopliae and M. acridum. PLoS Genet., 2011, 7: e1001264.
【23】 Jin K, Zheng X, Xia Y. Gene expression profiling via multigene concatemers. PLoS One. 2011, 6:e15711.
【24】 Cao Y., Li M., Xia Y. Mapmi contributes to growth, stress tolerance and virulence of the entomopathogenic fungus Metarhizium acridum, J.
Invert. Pathol., 2011, 108: 7-12.
【25】 Cao Y., Li K., Xia Y. Down-regulation of the pre-rRNA processing gene Mamrd1 decreases growth and virulence in the entomopathogenic fungus,
Metarhizium acridum. Res Microbiol, 2011, 162: 729-736.
【26】 Yang M, Jin K, Xia Y. MaFKS, a β-1,3-glucan synthase, is involved in cell wall integrity, hyperosmotic pressure tolerance and conidiation
in Metarhizium acridum. Curr Genet., 2011, 57:253-260.
【27】 Zheng XL. Xia YX. β-1,3-Glucan recognition protein (βGRP) is essential for resistance against fungal pathogen and opportunistic
pathogenic gut bacteria in Locusta migratoria manilensis. Developmental & Comparative Immunology, 2011, 36(3):602-609.
【28】 Leng YJ, Peng GX, Cao YQ, Xia YX (2011) Genetically altering the expression of neutral trehalase gene affects conidiospore thermotolerance
of the entomopathogenic fungus Metarhizium acridum. BMC Microbiology. 2011, 11:32
【39】 Zhang S, Xia Y, Kim B Keyhani NO. Two hydrophobins are involved in fungal spore coat rodlet layer assembly and each play distinct roles in
surface interactions, development and pathogenesis in the entomopathogenic fungus, Beauveria bassiana. Mol. Microbiol. 2011, 80:811-826.
【30】 Zhang C, Xia Y, Li Z. Identification of genes differentially expressed by Metarhizium anisopliae growing on Locusta migratoria wings using
suppression subtractive hybridization. Curr Microbiol. 2011, 62(5):1649-55.
【31】 Zhou X, Xia Y. Expression and characterization of recombinant Locusta migratoria manilensis acetylcholinesterase 1 in Pichia pastoris.
Protein Expr Purif. 2011, 77:62-67.
【32】 Peng GX, Xia YX. The mechanism of the mycoinsecticide diluent on the efficacy of the oil formulation of insecticidal fungus. Biocontrol,
2011, 56:893–902
Awards
Chongqing Technology Invention Award First Prize in 2009
Postgraduate training
Team : Six Master students; 6 Ph.D students; 3 Postdoctoral reseach associates
Contact information
Email：yuxianxia@cqu.edu.cn
