Department: Biological chemistry and molecular biology
Description: Research by the biological chemistry and molecular biology department in School of Life Sciences focuses on the genetic regulatory network of major chronical diseases such as malignant tumors and metabolic diseases, aiming to reveal new opportunities in the diagnosis and treatment of these critical healthcare challenges. The biological chemistry and molecular biology department have successfully developed multiple animal-based disease models using caenorhabditis elegans and mice to screen new gene targets that control tumorigenesis, tumor growth, invasion and metastasis as well as elucidating the molecular mechanisms underlying sugar/lipid metabolism. Through the convergence of medical science, cellular/molecular biology and material science, researchers of the biological chemistry and molecular biology department have made prominent progress in developing new nanobiomaterials for tumor therapy, which comprehensively elucidated their efficacy and safety in a clinical context. The research also presented emerging opportunities for the development of novel combinational immunotherapies and multimodal tumor theranostics, which holds promise for new breakthroughs against these major chronical diseases as well as fostering translational research in related areas. The results have been published on top-ranking journals with world renown such as Nature Comm, Angew.Chem.Int.Ed, Adv Mater, Cell metabolism, etc. Some of the members have also received the First-Class Award of Chongqing Natural Science Award.
Members: Prof. Shanshan Pang, Prof. Zhenghong Lin, Prof. Zhong Luo, Prof. Aimin Yang, Prof. Haibo Wu, Prof. Wenhui Zhao, Assoc. Prof. Lei Shi, Assoc. Prof. Menghuan Li, Assoc. Prof. Haiqing Tang.