师资队伍

 

 

姓 名：罗忠

 

罗忠，重庆大学生命科学学院教授、院长，获得国家自然科学基金委优秀青年基金项目、重庆市杰出青年基金项目和重庆市青年拔尖人才支持计划。一直从事肿瘤发生发展分子作用机制、抗肿瘤药物传输系统的设计与疗效评价、免疫工程化调控以及组织再生与修复的研究。以第一/通讯作者在Nat Commun（4篇）、Science Advances、Cell Rep（2篇）、Angew Chem（3篇）和Adv Mater等国内外高水平SCI期刊发表100余篇论文(平均影响因子12)，他引10000余次，授权专利10余项，入选全球顶尖科学家（前2%）。担任中国细胞生物学学会理事、中国生物物理学会微量元素分会常务委员/副秘书长、中国生物材料学会纳米生物材料分会/智能仿生材料分会/复合材料分会委员、重庆市细胞生物学学会副理事长等兼职；主持国自然优青/重大研究计划培育项目/面上项目、科技部重点研发子课题等20余项国家省部级项目，部分研究成果获得重庆市自然科学奖一等奖（第三），教学成果获得重庆大学教学成果特等奖、一等奖和二等奖等奖项。

 

 

2002年进入重庆邮电大学，获得学士学士（2006）；

2006年-2011年，进入重庆大学生物工程学院，获得“生物医学工程”博士学位（2011，硕博连读）。

• 2012.07—2015.09 新加坡南洋理工大学 化学与生物化学系 Research Fellowship

• 2015.10—2021.09 重庆大学生命科学学院 特聘研究员（百人计划）、博导

• 2021.10—至今   重庆大学生命科学学院 弘深优秀学者、教授、博导

一直从事肿瘤发生发展作用机制、免疫调控、合成生物材料、药物递送和组织修复的研究。以第一/通讯作者在Nat Commun(4篇)、Science Advances、Cell Rep(2篇)、Angew Chem和Adv Mater等国内外高水平SCI期刊发表100余篇论文(平均影响因子12)，他引11000 余次，授权专利10余项。主持国自然科学基金优秀青年基金/重大研究计划培育项目、科技部重点研发子课题等20余项国家/省部级项目，部分研究成果获得重庆市自然科学奖一等奖（第三），重庆大学教学成果奖一等奖和二等奖。

国家自然科学基金委优秀青年基金项目、重庆市杰出青年基金项目和重庆市青年拔尖人才支持计划

中国细胞生物学会理事

中国生物物理学会微量元素分会常务委员/副秘书长

中国生物材料学会纳米生物材料分会/智能仿生材料分会/复合材料分会委员

重庆市细胞生物学学会副理事长

重庆市抗癌协会副主任委员

国家骨科与运动康复临床医学研究中心学术委员会青年委员

 

 

 

1. Wenkai Wang#, Zhuo Cheng#, Miao Yu, Ke Liu, Hongli Duan, Yang Zhang, Xinle Huang, Menghuan Li, Changqing Li, Yan Hu*, Zhong Luo*, Minghan Liu*. Injectable ECM-mimetic dynamic hydrogels abolish ferroptosis-induced post-discectomy herniation through in-situ delivery of nucleus pulposus progenitor cell-derived exosomes. Nature Communications 2025, 16:3131.

2. Yinglong Wu, Lihe Sun, Xiaodong Zhang, Wenbin Zhong, Xiaokai Chen, Shihuai Wang, Yun Chen, Dongdong Wang, Ting He, Hongzhong Chen, Jingjing Guo, Fang Zeng*, Menghuan Li, Zhong Luo*, Shuizhu Wu*, Yanli Zhao*. Unnatural triggers converted from tetrazine-attached sialic acid for activation of optoacoustic imaging-guided cancer theranostics. Angew Chem Int Ed 2025, 64, 26:e202503850.

3. Haibing Wang, Yilong Dong, Jiayi Zhang, Haifeng Zhang, Junnian Chen, Siya Wang, Huocheng Yang, Menghuan Li, Yan Hu*, and Zhong Luo*. Living microecological microneedle patches enable proregenerative microenvironmental remodeling for promoting infected diabetic wound healing. ACS Nano 2025, 19, 23:21739-21756.

4. Haifeng Zhang#, Wei Zhou#, Haibing Wang, Jiayi Zhang, Huocheng Yang, Junnian Chen, Siya Wang, Weikang Zhao*, Menghuan Li*, Zhong Luo*. Hydrogel-based bioactive synthetic skin enables integrative stimulation of regenerative gas signaling and elimination of interfacial bacteria to promote burn wound healing. ACS Nano 2025, 19, 15:15002-15017.

5. Xinqiang Hu, Maohua Chen, Huocheng Yang, Hao Wei, Bikun Zhou, Menghuan Li, Zhong Luo*, Kaiyong Cai*, and Yan Hu*. Cascade biomineralization of geometrically tuned osteon-mimetic composite biovesicle-hydrogel coating improves Ti implant-assisted repair of osteoporotic bone fractures. ACS Nano 2025, doi:10.1021/acsnano.5c08912.

6. Xuemei Yao, Huocheng Yang, Sizhe Guo, Ying Liu, Qiqi Zhang, Zao Zhou, Menghuan Li*, Zhong Luo*. Radiation-triggerable bioreactors enable bioenergetic reprograming of cancer stem cell plasticity via targeted arginine metabolism disruption for augmented radio-immunotherapy. Biomaterials 2025, 322:123391.

7. Yuanyuan Fu, Ting Wang, Xinyue Ge, Hong Wen, Yang Fei, Menghuan Li*, Zhong Luo*. Orally-deliverable liposome-microgel complexes dynamically remodel intestinal environment to enhance probiotic ulcerative colitis therapy via TLR4 inhibition and tryptophan metabolic crosstalk. Biomaterials 2025, 321:123339.

8. Menghuan Li#, Yanan Li#, Xuemei Yao, Yingqi Liu, Kaiyong Cai, Huocheng Yang*, Zhong Luo*. Optically controllable nanoregulators enable tumor-specific pro-ferroptosis lipometabolic reprogramming for in-situ adjuvant-free vaccination. Biomaterials 2025, 317:213096.

9. Jinming He#, Xijiao Ren#, Qiqi Zhang, Shuang Wang, Zhongjun Li, Kaiyong Cai, Menghuan Li*, Yan Hu*, Qian Ran*, Zhong Luo*. Nanoradiosentizers with X ray-actuatable supramolecular aptamer building units for programmable immunostimulatory T cell engagement. Biomaterials 2025, 315: 122924.

10. Siya Wang, Yu Zhai, Minghan Liu*, Zhuo Cheng, Jiayi Zhang, Haifeng Zhang, Haibing Wang, Yan Hu*, Changqing Li*, Zhong Luo*. A hydrogel-based drug delivery system reduces inflammation and oxidative stress to alleviate intervertebral disc degeneration. Acta Biomaterialia 2025, 202: 229-244.

11. Lu Tan, Yanqiu Wang, Chenxi Huyan, Menghuan Li, Dong Liu, Minghan Liu, Zhong Luo*, Kaiyong Cai*, Yan Hu*. Mechanically-adaptive Janus hydrogel enhances scarless tendon healing with tissue-adhesion prevention. Acta Biomaterialia 2025, 202: 170-192.

12. Ting Wang#, Jie Chen#, Chuandong Shu#, Xinkun Shen, Yuanyuan Fu, Menghuan Li*, Zhong Luo*. Orally-administrable supramolecular probiotic capsules enable cooperative colon-targeted inflammation inhibition for ameliorating ulcerative colitis. Acta Biomaterialia 2025, 194: 396-410.

13. Shuohan He, Huanhuan Zhao, Maohua Chen, Menghuan Li, Yi Wu, Hang Chen, Yan Zheng, Zhong Luo*, Kaiyong Cai*, Yan Hu*. Bioglass-integrated dynamic hydrogels improve matrix-directed repair of cranial defects through cooperative mechano-biochemical regulation. Advanced Healthcare Materials 2025, 14(16): 2500134.

14. Hang Chen#, Lu Tan#, Liqi Li#, Yan Zheng, Menghuan Li, Shuohan He, Zhong Luo*, Kaiyong Cai*, Yan Hu*. Multifunctional layered microneedle patches enable transdermal angiogenesis and immunomodulation for scarless healing of thermal burn injuries. Materials Today Bio 2024, 29: 101359.

15. Yingqi Liu, Dan Tao, Menghuan Li*, Zhong Luo*. Biomaterial-mediated metabolic regulation of ferroptosis for cancer immunotherapy. Wiley Interdisciplinary Reviews-Nanomedicine And Nanobiotechnology 2024, 16(6): 2010.

16. Yilong Dong#, Yan Hu#, Xinqiang Hu#, Lingshuang Wang, Xinkun Shen, Hao Tian, Menghuan Li*, Zhong Luo*, Chunyuan Cai*. Synthetic nanointerfacial bioengineering of Ti implants: on-demand regulation of implant-bone interactions for enhancing osseointegration. Materials Horizons 2024, 12(3): 694-718.

17. Mubassir Khan#, Yilong Dong#, Razi Ullah, Menghuan Li, Qiping Huang, Yan Hu*, Li Yang*, Zhong Luo*. Recent advances in bacterium-based therapeutic modalities for melanoma treatment. Advanced Healthcare Materials 2024, 13(29): 202401076.

18. Yan Zheng#, Lu Tan#, Hang Chen, Shuohan He, Menghuan Li, Zhong Luo*, Kaiyong Cai*, Yan Hu*. Hierarchical integration of curcumin-loaded CaCO3 nanoparticles and black phosphorus nanosheets in core/shell nanofiber for cranial defect repair. Advanced Healthcare Materials 2024, 13(30): 01786.

19. Youbo Zhao#, Yang Fei#, Yang Zhao, Menghuan Li*, Yan Hu, Kaiyong Cai, Shu-Hong Yu, Zhong Luo*. Biomineralization-tuned nanounits reprogram the signal transducer and activator of transcription 3 signaling for ferroptosis-immunotherapy in cancer stem cells. ACS Nano 2024, 18(32): 21268-21287.

20. Xijiao Ren#, Rui Xue#, Yan Luo#, Shuang Wang, Xinyue Ge, Xuemei Yao, Liqi Li, Junxia Min, Menghuan Li*, Zhong Luo*, Fudi Wang*. Programmable melanoma-targeted radio-immunotherapy via fusogenic liposomes functionalized with multivariate-gated aptamer assemblies. Nature Communications 2024, 15(1): 49482-9.

21. Yingqi Liu, Yidan Qin, Bingbing Yang, Hongmei Zheng, Songlin Qiao*, Zhong Luo*, Rui Li.* Pseudorabies virus usurps non-muscle myosin heavy chain IIA to dampen viral DNA recognition by cGAS for antagonism of host antiviral innate immunity. Journal of Virology 2024, 98(5): 0048324.

22. Xuan Wang#, Qiqi Zhang, Jinming He, Yingqi Liu*, Menghuan Li*, Zhong Luo*, Youbo Zhao#, Xin Li. Liposomal STAT3-degrading PROTAC prodrugs promote anti-hepatocellular carcinoma immunity via chemically reprogramming cancer stem cells. Nano Letters 2024, 24(16): 4858-4868.

23. Lu Tan, Yan Hu, Xi Chen, Yanqiu Wang, Menghuan Li, Dong Liu, Minghan Liu, Zhong Luo*, Kaiyong Cai*, Yan Hu*. Mechanically robust hemostatic hydrogel membranes with programmable strain-adaptive microdomain entanglement for wound treatment in dynamic tissues. Biomaterials 2024, 18(11): 8360-8382.

24. Yanqiu Wang#, Lu Tan#, Wanqian Zhang#, Yi Yang, Changqing Li, Hongli Li, Kaiyong Cai,Yan Hu*, Zhong Luo*, Minghan Liu*. Injectable dynamic hydrogel with responsive mechanical reinforcing ability reverses intervertebral disc degeneration by suppressing ferroptosis and restoring matrix homeostasis. Advanced Functional Materials 2023, 34(14): 2310416.

25. Qiqi Zhang#, Xuan Wang#, Yuanyuan Zhao, Zhuo Cheng, De Fang, Yingqi Liu*, Gan Tian*, Menghuan Li*, Zhong Luo*. Nanointegrative in situ reprogramming of tumor-intrinsic lipid droplet biogenesis for low-dose radiation-activated ferroptosis immunotherapy. ACS Nano 2023, 17: 25419-25438.

26. Xijiao Ren, Zhuo Cheng, Jinming He, Xuemei Yao, Yingqi Liu, Kaiyong Cai, Menghuan Li*, Yan Hu*, Zhong Luo*. Inhibition of glycolysis-driven immunosuppression with a nano-assembly enhances response to immune checkpoint blockade therapy in triple negative breast cancer. Nature Communications 2023, 14: 7021.

27. Yingqi Liu, Xuemei Yao, Youbo Zhao, De Fang, Lei Shi, Li Yang, Guanbin Song, Kaiyong Cai, Liqi Li, Qin Deng, Menghuan Li*, Zhong Luo*. Mechanotransduction in response to ecm stiffening impairs cGAS immune signaling in tumor cells. Cell Reports 2023, 42: 113213.

28. Lu Tan, Menghuan Li, Hang Chen, Yuchen Zhang, Yuan Liu, Maohua Chen, Zhong Luo*, Kaiyong Cai*, Yan Hu*. Dynamic hydrogel with environment-adaptive autonomous wound-compressing ability enables rapid hemostasis and inflammation amelioration for hemorrhagic wound healing. Nano Today 2023, 52: 101962.

29. Zhuo Cheng, Chencheng Xue, Minghan Liu, Zhiming Cheng, Gan Tian, Menghuan Li, Rui Xue, Xuemei Yao, Yuan Zhang*, Zhong Luo*. Injectable microenvironment-responsive hydrogels with redox-activatable supramolecular prodrugs mediate ferroptosis-immunotherapy for postoperative tumor treatment. Acta Biomaterialia 2023, 169: 289-305.

30. Jiawu Yu, Yuchen Zhang, Liqi Li, Yang Xiang, Xuemei Yao, Youbo Zhao, Kaiyong Cai, Menghuan Li*, Zhongjun Li*, Zhong Luo*. Coordination-driven FBXW7 DNAzyme-Fe nanoassembly enables a binary switch of breast cancer cell cycle checkpoint responses for enhanced ferroptosis-radiotherapy. Acta Biomaterialia 2023, 169: 434-450.

31. Yuan Zhang, Zhuo Cheng, Zaiyang Liu, Xinkun Shen, Chunyuan Cai*, Menghuan Li*, Zhong Luo*. Functionally tailored metal–organic framework coatings for mediating Ti implant osseointegration. Advanced Science 2023, 10: 202303958.

32. Yan Huang, Maowen Chen, Yiding Shen, Xinkun Shen*, Menghuan Li, Yanan Li, Yuan Liu, Kaiyong Cai, Zhong Luo*, Yan Hu*. Bone-targeting cell membrane-engineered CaCO3-based nanoparticles restore local bone homeostasis for microenvironment-responsive osteoporosis treatment. Chemical Engineering Journal 2023, 470: 144145.

33. Huocheng Yang#, Xuemei Yao#, Yingqi Liu, Xinkun Shen*, Menghuan Li*, Zhong Luo*. Ferroptosis nanomedicine: Clinical challenges and opportunities for modulating tumor metabolic and immunological landscape. ACS Nano 2023, 17: 15328-15353.

34. Maohua Chen, Menghuan Li, Xijiao Ren, Fei Zhou, Yanan Li, Lu Tan, Zhong Luo*, Kaiyong Cai*, Yan Hu*. Dnazyme nanoconstruct-integrated autonomously-adaptive coatings enhance titanium-implant osteointegration by cooperative angiogenesis and vessel remodeling. ACS Nano 2023, 17: 15942-15961.

35. Xingwei Ding#, Wenyan Jiang#, Menghuan Li, Shiyu Xiong, Wei Wei, Mingzhuo Liu, Hongbo Xin*, Zhong Luo*, Yanli Zhao*. An ROS/DAMP dual-scavenging nanomedicine for normalizing macrophage polarization and microbiome in colitis. Nano Today 2023, 51: 101924.

36. Xinyue Ge#, Hong Wen#, Yang Fei, Rui Xue, Zhuo Cheng, Yanan Li, Kaiyong Cai, Liqi Li*, Menghuan Li*, Zhong Luo*. Structurally dynamic self-healable hydrogel cooperatively inhibits intestinal inflammation and promotes mucosal repair for enhanced ulcerative colitis treatment. Biomaterials 2023, 299: 122184.

37. Yingqi Liu, Yang Fei, Xuan Wang, Bingbing Yang, Menghuan Li*, Zhong Luo*. Biomaterial-enabled therapeutic modulation of cGAS-STING signaling for enhancing antitumor immunity. Molecular Therapy 2023, 31: 1938-1959.

38. Tingting He, Lu Wang, Shuangquan Gou, Lu Lu, Genhua Liu, Kui Wang, Yulu Yang, Qiaojian Duan,Wenbo Geng, Peng Zhao*, Zhong Luo*, Kaiyong Cai*. Enhanced immunogenic cell death and antigen presentation via engineered bifidobacterium bifidum to boost chemo-immunotherapy. ACS Nano 2023, 17: 9953-9971.

39. Zhuo Cheng#, Yan Hu#, Yingqi Liu, Xuan Wang, Rui Xue, Kaiyong Cai, Liqi Li*, Menghuan Li*, Zhong Luo*. Engineered in-situ-forming biomimetic hydrogel with self-regulated immunostimulatory capacity promotes postoperative tumor treatment. Fundamental Research 2023, doi:10.1016/j.fmre.2023.02.029.

40. Yuan Liu#, Lu Tan#, Yan Huang, Maohua Chen, Menghuan Li, Kaiyong Cai*, Zhong Luo*, Yan Hu*. Multifunctional antibiotics-free hydrogel dressings with self-regulated nitric oxide-releasing kinetics for improving open wound healing. Journal of Materials Chemistry B 2023, 11: 3650-3668.

41. Qiwen Guan#, Xuan Wang#, Danfeng Cao, Menghuan Li, Zhong Luo*, Xiaoyuan Mao*. Calcium phosphate-based nanoformulation selectively abolishes phenytoin resistance in epileptic neurons for ceasing seizures. Small 2023, 19: 2300395.

42. Hong Wen#, Liqi Li#, Xinyue Ge, Yang Fei, Yanan Li, Menghuan Li*, Weidong Xiao*, Zhong Luo*. Hydrogel-based artificial mucosa restores local immune and microbial homeostasis for treating ulcerative colitis. Advanced Functional Materials 2023, 33: 2212566.

43. Yingqi Liu#, Yunyun Wu#, Zhong Luo*, Menghuan Li*. Designing supramolecular self-assembly nanomaterials as stimuli-responsive drug delivery platforms for cancer therapy. iScience 2023, 26: 106279.

44. Fei Zhou, Menghuan Li, Maohua Chen, Maowen Chen, Xiaodong Chen, Zhong Luo*, Kaiyong Cai*, Yan Hu*. Redox homeostasis strategy for inflammatory macrophage reprogramming in rheumatoid arthritis based on ceria oxide nanozyme-complexed biopolymeric micelles. ACS Nano 2023, 17: 4358-4372.

45. Youbo Zhao#, Menghuan Li#, Zhong Luo*, Min Su*, Chao Yu*. Recent progress in the therapeutic modulation of lactate for cancer treatment. Advanced Therapeutics 2022, 6: 2200254.

46. Xiaoyuan Mao*, Xuan Wang, Mingzhu Jin, Qin Li, Jining Jia, Menghuan Li, Honghao Zhou, Zhaoqian Liu*, Weilin Jing*, Yanli Zhao*, Zhong Luo*. Critical involvement of lysyl oxidase in seizure- induced neuronal damage through ERK-Alox5-Dependent ferroptosis and its therapeutic implications. Acta Pharmaceutica Sinica B 2022, 12: 3513-3528.

47. Maohua Chen, Menghuan Li, Yujia Wei, Chencheng Xue, Maowen Chen, Yang Fei, Lu Tan, Zhong Luo*, Kaiyong Cai*, Yan Hu*. ROS-activatable biomimetic interface mediates in-situ bioenergetic remodeling of osteogenic cells for osteoporotic bone repair. Biomaterials 2022, 291: 121878.

48. Chencheng Xue#, Hui Zhang#, Xuan Wang, Haoyu Du, Lu Lu, Yang Fei, Yanan Li, Yuchen Zhang, Menghuan Li*, Zhong Luo*. Bio-inspired engineered ferritin-albumin nanocomplexes for targeted ferroptosis therapy. Journal of Controlled Release 2022, 351: 581-596.

49. Yujia Wei#, Maohua Chen#, Menghuan Li, Dong Wang, Kaiyong Cai*, Zhong Luo*, Yan Hu*. Aptamer/hydroxyapatite-functionalized titanium substrate promotes implant osseointegration via recruiting mesenchymal stem cells. ACS Applied Materials & Interfaces 2022, 14: 42915-42930.

50. Xuan Wang#, Yingqi Liu#, Chencheng Xue, Yan Hu, Yuanyuan Zhao, Kaiyong Cai, Menghuan Li*, Zhong Luo*. A protein-based cGAS-STING nanoagonist enhances T cell-mediated anti-tumor immune responses. Nature Communications 2022, 13: 5685.

51. Maowen Chen#, Dong Wang#, Menghuan Li, Ye He, Tingting He, Maohua Chen, Yan Hu*, Zhong Luo*, Kaiyong Cai*. Nanocatalytic biofunctional MOF coating on titanium implants promotes osteoporotic bone regeneration through cooperative proosteoblastogenesis msc reprogramming. ACS Nano 2022, 16: 15397-15412.

52. Lu Tan, Menghuan Li, Zhong Luo*, Kaiyong Cai*, Yan Hu*. Black phosphorus biomaterials for photo-controlled bone tissue engineering. Composites Part B-Engineering 2022, 246: 110245.

53. Dong Wang, Mao-Wen Chen, Yu-Jia Wei, Wen-Bo Geng, Yan Hu*, Zhong Luo*, Kaiyong Cai*. Construction of wogonin nanoparticle-containing strontium-doped nanoporous structure on titanium surface to promote osteoporosis fracture repair. Advanced Healthcare Materials 2022, 11: 2201405.

54. Yanhua Hou, Yang Fei, Zehong Liu, Yingqi Liu*, Menghuan Li*, Zhong Luo*. Black phosphorous nanomaterials as a new paradigm for postoperative tumor treatment regimens. Journal of Nanobiotechnology 2022, 20: 366.

55. Zhong Luo#, Xuemei Yao#, Menghuan Li#, De Fang, Yang Fei, Zhuo Cheng, Yingying Xu*, Bo Zhu*. Modulating tumor physical microenvironment for fueling Car-T cell therapy. Advanced Drug Delivery Reviews 2022, 185: 114301.

56. Maohua Chen#, Yuting Sun#, Yanhua Hou, Zhong Luo*, Menghuan Li, Yujia Wei, Maowen Chen, Lu Tan, Kaiyong Cai*, Yan Hu*. Constructions of ROS-responsive titanium-hydroxyapatite implant for mesenchymal stem cell recruitment in Peri-Implant space and bone formation in osteoporosis microenvironment. Bioactive Materials 2022, 18: 56-71.

57. Wenbo Geng#, Maowen Chen#, Bailong Tao, Rong Wang, Dong Wang, Ke Li, Chuanchuan Lin, Xuezhe Liu, Pengfei Gao, Zhong Luo*, Kaiyong Cai*. Cell-free DNA depletion via cell-penetrating poly(disulfide)s for rheumatoid arthritis therapy. Applied Materials Today 2022, 26: 101351.

58. Beibei Yan#, Chencheng Xue#, Menghuan Li#, Liang Dong, Yang Zhao, Zhong Luo*, Shu-Hong Yua*. All-in-one hollow nanoformulations enabled imaging-guided Mn- amplified chemophototherapy against hepatocellular carcinoma. Nano Today 2022, 43: 101382.

59. Xuemei Yao#, Wei Li#, Liqi Li*, Menghuan Li, Youbo Zhao, De Fang, Xiaohua Zeng*, Zhong Luo*. Ythdf1 upregulation mediates hypoxia-dependent breast cancer growth and metastasis through regulating PKM2 to affect glycolysis. Cell Death & Disease 2022, 13: 258.

60. Yanan Li#, Menghuan Li#, Li Liu, Chencheng Xue, Yang Fei, Xuan Wang, Yuchen Zhang, Kaiyong Cai, Yanli Zhao*, Zhong Luo*. Cell-specific metabolic reprogramming of tumors for bioactivatable ferroptosis therapy. ACS Nano 2022, 16: 3965-3984.

61. Ke Li, Chuanchuan Lin, Menghuan Li, Kun Xu, Ye He, Yulan Mao, Lu Lu, Wenbo Geng, Xuemin Li, Zhong Luo*, Kaiyong Cai*. Multienzyme-like reactivity cooperatively impairs glutathione peroxidase 4 and ferroptosis suppressor protein 1 pathways in triple-negative breast cancer for sensitized ferroptosis therapy. ACS Nano 2022, 16: 2381-2398.

62. Lu Tan, Yan Hu*, Menghuan Li, Yuchen Zhang, Chencheng Xue, Maohua Chen, Zhong Luo*, Kaiyong Cai*. Remotely-activatable extracellular matrix-mimetic hydrogel promotes physiological bone mineralization for enhanced cranial defect healing. Chemical Engineering Journal 2022, 431: 133382.

63. Yuchen Zhang, Liqi Li, Yanan Li, Yang Fei, Chencheng Xue, Xuemei Yao, Youbo Zhao, Xuan Wang, Menghuan Li*, Zhong Luo*. An ROS-activatable nanoassembly remodulates tumor cell metabolism for enhanced ferroptosis therapy. Advanced Healthcare Materials 2021, 11: 2101702.

64. Xuemei Yao#, Wei Li#, De Fang, Chuyu Xiao, Xiao Wu, Menghuan Li*, Zhong Luo*. Emerging roles of energy metabolism in ferroptosis regulation of tumor cells. Advanced Science 2021, 8: 2100997.

65. Hong Wen#, Yang Fei#, Ruisi Cai, Xuemei Yao, Yanan Li, Xuan Wang, Chencheng Xue, Yan Hu, Menghuan Li*, Zhong Luo*. Tumor-activatable biomineralized nanotherapeutics for integrative glucose starvation and sensitized metformin therapy. Biomaterials 2021, 278: 121165.

66. Xuan Wang#, Yuanyuan Zhao#, Yan Hu, Yang Fei, Youbo Zhao, Chencheng Xue, Kaiyong Cai, Menghuan Li*, Zhong Luo*. Activatable biomineralized nanoplatform remodels the intracellular environment of multidrug-resistant tumors for enhanced ferroptosis/apoptosis therapy. Small 2021, 17: 2102269.

67. Ke Li, Kun Xu, Ye He, Lu Lu, Yulan Mao, Pengfei Gao, Genhua Liu, Jing Wu, Yuchen Zhang, Yang Xiang, Zhong Luo*, Kaiyong Cai*. Functionalized tumor-targeting nanosheets exhibiting Fe (II) overloading and GSH consumption for ferroptosis activation in liver tumor. Small 2021, 17: 2102046.

68. Lu Lu, Genhua Liu, Chuanchuan Lin, Ke Li, Tingting He, Jixi Zhang, Zhong Luo*, and Kaiyong Cai*. Mitochondrial metabolism targeted nanoplatform for efficient triple-negative breast cancer combination therapy. Advanced Healthcare Materials 2021, 10: 2100978.

69. Li Liu, Liqi Li, Menghuan Li*, Zhong Luo*. Autophagy-dependent ferroptosis as a therapeutic target in cancer. Chem medchem 2021, 16: 2942-2950.

70. Maowen Chen#, Bailong Tao#, Yan Hu*, Menghuan Li, Maohua Chen, Lu Tan, Zhong Luo*, Kaiyong Cai*. Enhanced biocompatibility and osteogenic differentiation of mesenchymal stem cells of titanium by sr-ga clavate double hydroxides. Journal of Materials Chemistry B 2021, 9: 6029-6036.

71. Maohua Chen, Yan Hu*, Yanhua Hou, Yuting Sun, Maowen Chen, Menghuan Li, Lu Tan, Zhong Luo*, Kaiyong Cai*. Construction of a reactive oxygen species-responsive biomimetic multilayered titanium implant for in situ delivery of α-melanocyte-stimulating hormone to improve bone remolding in osteoporotic rats. Applied Materials Today 2021, 23: 101059.

72. Zhiwen Deng, Menghuan Li, Yan Hu*, Ye He, Bailong Tao, Zhang Yuan, Rong Wang, Maowen Chen, Zhong Luo*, Kaiyong Cai*. Injectable biomimetic hydrogels encapsulating gold/metal-organic frameworks nanocomposites for enhanced antibacterial and wound healing activity under visible light actuation. Chemical Engineering Journal 2021, 420: 129668.

73. Maowen Chen, Yan Hu*, Yanhua Hou, Menghuan Li, Lu Tan, Maohua Chen, Wenbo Geng, Bailong Tao, Hong Jiang, Zhong Luo*, Kaiyong Cai*. Magnesium/gallium-layered nanosheets on titanium implants mediate osteogenic differentiation of mscs and osseointegration under osteoporotic condition. Chemical Engineering Journal 2021, 427: 130982.

74. Lei Shi#, Yingqi Liu#, Menghuan Li*, Zhong Luo*. Emerging roles of ferroptosis in the tumor immune landscape: from danger signals to anti-tumor immunity. FEBS Journal 2021, 13: 3655-3665.

75. Rui Zeng#, Tingting He#, Lu Lu, Ke Li, Zhong Luo*, Kaiyong Cai*. Ultra-thin metal-organic framework nanosheets for chemo-photodynamic synergistic therapy. Journal of Materials Chemistry B 2021, 9: 4143-4153.

76. Xuan Wang#, Youbo Zhao#, Lei Shi, Yan Hu, Guanbin Song, Kaiyong Cai, Menghuan Li*, Zhong Luo*. Tumor-targeted disruption of lactate transport with reactivity-reversible nanocatalysts to amplify oxidative damage. Small 2021, 17: 2100130.

77. Chencheng Xue#, Menghuan Li#, Linawati Sutrisno, Beibei Yan, Yang Zhao, Yan Hu, Kaiyong Cai, Yanli Zhao, Shuhong Yu*, Zhong Luo*. Bioresorbable scaffolds with biocatalytic chemotherapy and in situ microenvironment modulation for postoperative tissue repair. Advanced Functional Materials 2021, 31: 2008732.

78. Chencheng Xue#, Menghuan Li#, Changhuang Liu#, Yanan Li, Yang Fei, Yan Hu, Kaiyong Cai, Yanli Zhao, Zhong Luo*. NIR-actuated remote activation of ferroptosis in target tumor cells through a photothermally responsive iron-chelated biopolymer nanoplatform. Angewandte Chemie International Edition 2021, 60: 8938-8947.

79. Chencheng Xue#, Linawati Sutrisno#, Menghuan Li#, Wei Zhu, Yang Fei, Changhuang Liu, Xuan Wang, Kaiyong Cai, Yan Hu*, Zhong Luo*. Implantable multifunctional black phosphorus nanoformulation-deposited biodegradable scaffold for combinational photothermal/ chemotherapy and wound healing. Biomaterials 2021, 269: 120623.

80. Ke Li, Chuanchuan Lin, Ye He, Lu Lu, Kun Xu, Bailong Tao, Zengzilu Xia, Rui Zeng, Yulan Mao, Zhong Luo*, Kaiyong Cai*. Engineering of cascade-responsive nanoplatform to inhibit lactate efflux for enhanced tumor chemo-immunotherapy. ACS Nano 2020, 14: 14164-14180.

81. Youbo Zhao, Menghuan Li, Xuemei Yao, Yang Fei, Zhenghong Lin, Zhengguo Li, Kaiyong Cai, Yanli Zhao, Zhong Luo*. HCAR1/MCT1 regulates tumor ferroptosis through the lactate-mediated ampk-scd2 activity and its therapeutic implications. Cell Reports 2020, 33: 108487.

82. Wee Kong Ong#, Xuemei Yao#, Deblin Jana, Menghuan Li, Yanli Zhao*, Zhong Luo*. Efficient production of reactive oxygen species from Fe3O4/ZnPC coloaded nanoreactor for cancer therapeutics in vivo. Small Structures 2020, 1: 2000065.

83. Maowen Chen, Yan Hu*, Yanhua Hou, Menghuan Li, Maohua Chen, Lu Tan, Caiyun Mu, Bailong Tao, Zhong Luo*, Kaiyong Cai*. Osteogenesis regulation of mesenchymal stem cellsviaautophagy induced by silica-titanium composite surfaces with different mechanical moduli. Journal of Materials Chemistry B 2020, 8: 9314-9324.

84. Yanan Li#, Linawati Sutrisno#, Yanhua Hou, Yang Fei, Chengcheng Xue, Yan Hu, Menghuan Li*, Zhong Luo*. A redox-activatable biopolymer-based micelle for sequentially enhanced mitochondria-targeted photodynamic therapy and hypoxia-dependent chemotherapy. Chemical Communications 2020, 56: 9978-9981.

85. Caiyun Mu, Ye He, Yan Hu∗, Menghuan Li, Maowen Chen, Rong Wang, Yang Xiang, Zhong Luo∗, Kaiyong Cai∗. Construction of chemokine substance p-embedded biomimetic multilayer onto bioactive magnesium silicate-titanium implant for bone regeneration. Applied Materials Today 2020, 20: 100777.

86. Xuan Wang#, Menghuan Li#, Yanhua Hou, Yanan Li, Xuemei Yao, Chencheng Xue, Yang Fei, Yang Xiang, Kaiyong Cai, Yanli Zhao*, Zhong Luo*. Tumor-microenvironment-activated in situ self-assembly of sequentially responsive biopolymer for targeted photodynamic therapy. Advanced Functional Materials 2020, 30: 2000229.

87. Yang Fei#, Menghuan Li#, Yanan Li, Xuan Wang, Chencheng Xue, Zuosu Wu, Jiaying Xu, Zilu Xiazeng*, Kaiyong Cai*, Zhong Luo*. Hierarchical integration of degradable mesoporous silica nanoreservoirs and supramolecular dendrimer complex as a general-purpose tumor-targeted biomimetic nanoplatform for gene/small- molecule anticancer drug co-delivery. Nanoscale 2020, 12(30): 16102-16112.

88. Xuemei Yao#, Menghuan Li#, Bing Li#, Chencheng Xue, Kaiyong Cai, Yanli Zhao*, Zhong Luo*. Tumor-targeted upconverting nanoplatform constructed by host-guest interaction for near-infrared-light-actuated synergistic photodynamic-/ chemotherapy. Chemical Engineering Journal 2020, 390: 124516.

89. Ke Li, Menghuan Li, Zhong Luo*, Yulan Mao, Yonglin Yu, Ye He, Jun Zhou,Yang Fei, Yuxia Pei, Kaiyong Cai*. Overcoming the hypoxia-induced drug resistance in liver tumor by the concurrent use of apigenin and paclitaxel. Biochemical and Biophysical Research Communications, 2020, 526: 321-327.

90. Lu Lu, Bing Li, Chuanchuan Lin, Ke Li, Genhua Liu, Zengzilu Xia, Zhong Luo*,Kaiyong Cai*. Redox-responsive amphiphilic camptothecin prodrug nanoparticles for targeted liver tumor therapy. JournaL of Materials Chemistry B 2020, 8: 3918-3928.

91. Youbo Zhao#, Hui Zhang#, Yanhua Hou, Menghuan Li*, Zhong Luo*. Progress toward safe tumor diagnosis and therapy via degradable inorganic nanomaterials constructed with metabolically safe elements. ACS Applied Nano Materials 2020, 3: 1028-1042.

92. Lu Tan, Yan Hu*, Yanhua Hou, Maowen Chen, Chencheng Xue, Maohua Chen, Yuting Sun, Caiyun Mu, Zhong Luo*, Kaiyong Cai*. Osteogenic differentiation of mesenchymal stem cells by silica/calcium micro-galvanic effects on the titanium surface. Journal of Materials Chemistry B 2020, 8: 2286-2295.

93. Chencheng Xue#, Menghuan Li#, Yang Zhao#, Jun Zhou, Yan Hu, Kaiyong Cai, Yanli Zhao, Shuhong Yu*, Zhong Luo*. Tumor microenvironment-activatable Fe-doxorubicin preloaded amorphous CaCO3 nanoformulation triggers ferroptosis in target tumor cells. Science Advances 2020, 6: eaax1346.

94. Menghuan Li#, Hui Zhang#, Yanhua Hou, Xuan Wang, Chencheng Xue, Wei Li, Kaiyong Cai, Yanli Zhao*, Zhong Luo*. State-of-the-art iron-based nanozymes for biocatalytic tumor therapy. Nanoscale Horizons 2020, 5: 202-217.

95. Lu Lua#, Xiaojing Zhao#, Tiwei Fu, Ke Li, Ye He, Zhong Luo*, Liangliang Dai, Rui Zeng, Kaiyong Cai∗. An iRGD-conjugated prodrug micelle with blood-brain-barrier penetrability for anti-glioma therapy. Biomaterials 2020, 230: 119666.

96. Ke Li, Lu Lu, Chencheng Xue, Ju Liu, Ye He, Jun Zhou, Zengzilu Xia, Liangliang Dai*, Zhong Luo*, Yulan Mao, Kaiyong Cai*. Polarization of tumor-associated macrophage phenotype via porous hollow iron nanoparticles for tumor immunotherapy in vivo. Nanoscale 2020, 12: 130-144.

97. Menghuan Li, Zhong Luo*, Zhihong Peng, Kaiyong Cai*. Cascade-amplification of therapeutic efficacy: an emerging opportunity in cancer treatment. Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology 2019, 11: e1555.

98. Soo Zeng Fiona Phua#, Chencheng Xue#, Wei Qi Lim, Guangbao Yang, Hongzhong Chen, Yuanyuan Zhang, Chintya Fransisca Wijaya, Zhong Luo*, Yanli Zhao*. Light-responsive prodrug-based supramolecular nanosystems for site-specific combination therapy of cancer. Chemistry of Materials 2019, 31: 3349-3358.

99. Lu Lu, Xinkun Shen, Bailong Tao, Chuanchuan Lin, Ke Li, Zhong Luo*, Kaiyong Cai*. The nanoparticle-facilitated autophagy inhibition of cancer stem cells for improved chemotherapeutic effects on glioblastomas. Journal of Materials Chemistry B 2019, 7: 2054-2062.

100. Youbo Zhao#, Wei Li#, Menghuan Li*, Yan Hu, Hui Zhang, Guanbin Song, Li Yang, Kaiyong Cai, Zhong Luo*. Targeted inhibition of MCT4 disrupts intracellular pH homeostasis and confers self-regulated apoptosis on hepatocellular carcinoma. Experimental Cell Research 2019, 384: 111591.

101. Maowen Chen, Yan Hu*, Yanhua Hou, Menghuan Li, Maohua Chen, Caiyun Mu, Bailong Tao, Wei Zhu, Zhong Luo*, Kaiyong Cai*. Differentiation regulation of mesenchymal stem cells via autophagy induced by structurally-different silica based nanobiomaterials. Journal of Materials Chemistry B 2019, 7: 2657-2666.

102. Jun Zhou, Chencheng Xue, Yanhua Hou, Menghuan Li*, Yan Hu, Qiufang Chen, Yanan Li, Ke Li, Guanbin Song, Kaiyong Cai*, Zhong Luo*. Oxygenated theranostic nanoplatforms with intracellular agglomeration behavior for improving the treatment efficacy of hypoxic tumors. Biomaterials 2019, 197: 129-145.

103. Yuxia Pei#, Menghuan Li#, Yanhua Hou, Yan Hu*, Guangyu Chu, Liangliang Dai, Ke Li, Yuxin Xing, Bailong Tao, Yonglin Yu, Chencheng Xue, Ye He, Zhong Luo*, Kaiyong Cai*. An autonomous tumor-targeted nanoprodrug for reactive oxygen species-activatable dual-cytochrome c/doxorubicin antitumor therapy. Nanoscale 2018, 10: 11418-11429.

104. Jun Zhou, Menghuan Li, Yanhua Hou, Zhong Luo*, Qiufang Chen, Hexu Cao, Runlan Huo, Chencheng Xue, Linawati Sutrisno, Lan Hao, Yang Cao, Haitao Ran, Lu Lu, Ke Li, Kaiyong Cai*. Engineering of a nanosized biocatalyst for combined tumor starvation and low-temperature photothermal therapy. ACS Nano 2018, 12: 2858-2872.

105. Menghuan Li, Zhong Luo*，Yanli Zhao*. Recent advancements in 2d nanomaterials for cancer therapy. Science China-Chemistry 2018, 61: 1214-1226.

106. Menghuan Li, Zhong Luo*, Yanli Zhao*. Self-assembled hybrid nanostructures: versatile multifunctional nanoplatforms for cancer diagnosis and therapy. Chemistry of Materials 2018, 30: 25-53.

107. Jun Zhou#, Menghuan Li#, Wei Qi Lim#, Zhong Luo*, Soo Zeng Fiona Phu, Runlan Huo, Liqi Li, Ke Li, Liangliang Dai, Junjie Liu, Kaiyong Cai, Yanli Zhao*. A transferrin-conjugated hollow nanoplatform for redox-controlled and targeted chemotherapy of tumor with reduced inflammatory reactions. Theranostics 2018, 8: 518-532.

108. Menghuan Li, Zhong Luo*, Zhining Xi, Xinkun Shen, Kaiyong Cai*. Time-sequenced drug delivery approaches towards effective chemotherapeutic treatment of glioma. Materials Horizons 2017, 4: 977-996.

109. Menghuan Li, Zhong Luo*, Yanli Zhao*. Hybrid nanoparticles as drug carriers for controlled chemotherapy of cancer. Chemical Record 2016, 16: 1833-1851.

110. Ling Huang#, Zhong Luo#, Yan Hu*, Xinkun Shen, Menghuan Li, Liqi Li, Yuan Zhang, Weihu Yang, Peng Liu, Kaiyong Cai*. Enhancement of local bone remodeling in osteoporotic rabbits by biomimic multilayered structures on Ti6al4v implants. Journal of Biomedical Materials Research Part A 2016, 104: 1437-1451.

111. Zhong Luo#, Yan Hu#, Renlong Xin, Beilu Zhang, Jinghua Li, Xingwei Ding, Yanhua Hou, Li Yang, Kaiyong Cai*. Surface functionalized mesoporous silica nanoparticles with natural proteins for reduced immunotoxicity. Journal of Biomedical Materials Research Part A 2014, 102: 3781-3794.  

112. Zhong Luo, Yan Hu*, Kaiyong Cai, Xingwei Ding, Quan Zhang, Menghuan Li, Xing Ma, Beilu Zhang, Yongfei Zeng, Peizhou Li, Jinghua Li, Junjie Liu, Yanli Zhao*. Intracellular redox-activated anticancer drug delivery by functionalized hollow mesoporous silica nanoreservoirs with tumor specificity. Biomaterials 2014, 35: 7951-7962.    

113. Zhong Luo, Xingwei Ding, Yan Hu, Shaojue Wu, Yang Xiang, Yongfei Zeng, Beilu Zhang, Hong Yan, Huacheng Zhang, Liangliang Zhu, Junjie Liu, Jinghua Li, Kaiyong Cai*, Yanli Zhao*. Engineering a hollow nanocontainer platform with multifunctional molecular machines for tumor-targeted therapy in vitro and in vivo. ACS Nano 2013, 7:10271-10284.    

114. Zhong Luo, Kaiyong Cai*, Yan Hu, Jinghua Li, Xingwei Ding, Beilu Zhang, Dawei Xu, Weihu Yang, Peng Liu. Redox-responsive molecular nanoreservoirs for controlled intracellular anticancer drug delivery based on magnetic nanoparticles. Advanced Materials 2012, 24:431-435.    

115. Zhong Luo, Kaiyong Cai*, Yan Hu, Beilu Zhang, Dawei Xu. Cell-specific intracellular anticancer drug delivery from mesoporous silica nanoparticles with ph sensitivity. Advanced Healthcare Materials 2012, 1(3): 321-325.

116. Zhong Luo ,  Kaiyong Cai*,  Beilu Zhang,  Lin Duan ,  Aiping Liu,  Duan Gong. Application of mesoporous silica nanoreservoir in smart drug controlled release systems. Progress in Chemistry 2011, 23: 2326-2338.

117. Zhong Luo, Kaiyong Cai*, Yan Hu, Li Zhao, Peng Liu, Lin Duan, and Weihu Yang. Mesoporous silica nanoparticles end-capped with collagen: redox-responsive nanoreservoirs for targeted drug delivery. Angewandte Chemie International Edition 2011, 50: 640-643.