姓 名：罗忠
罗忠，重庆大学生命科学学院教授、院长，获得国家自然科学基金委优秀青年基金项目、重庆市杰出青年基金项目和重庆市青年拔尖人才支持计划。一直从事肿瘤发生发展分子作用机制、抗肿瘤药物传输系统的设计与疗效评价、免疫工程化调控以及组织再生与修复的研究。以第一/通讯作者在Nat Commun（4篇）、Science Advances、Cell Rep（2篇）、Angew Chem（3篇）和Adv Mater等国内外高水平SCI期刊发表100余篇论文(平均影响因子12)，他引10000余次，授权专利10余项，入选全球顶尖科学家（前2%）。担任中国细胞生物学学会理事、中国生物物理学会微量元素分会常务委员/副秘书长、中国生物材料学会纳米生物材料分会/智能仿生材料分会/复合材料分会委员、重庆市细胞生物学学会副理事长等兼职；主持国自然优青/重大研究计划培育项目/面上项目、科技部重点研发子课题等20余项国家省部级项目，部分研究成果获得重庆市自然科学奖一等奖（第三），教学成果获得重庆大学教学成果特等奖、一等奖和二等奖等奖项。
教育背景
2002年进入重庆邮电大学，获得学士学士（2006）；
2006年-2011年，进入重庆大学生物工程学院，获得“生物医学工程”博士学位（2011，硕博连读）。
工作经历
2012.07—2015.09 新加坡南洋理工大学 化学与生物化学系 Research Fellowship
2015.10—2021.09 重庆大学生命科学学院 特聘研究员（百人计划）、博导
2021.10—至今 重庆大学生命科学学院 弘深优秀学者、教授、博导
研究领域及奖项
一直从事肿瘤发生发展作用机制、免疫调控、合成生物材料、药物递送和组织修复的研究。以第一/通讯作者在Nat Commun(4篇)、Science Advances、Cell Rep(2篇)、Angew Chem和Adv Mater等国内外高水平SCI期刊发表100余篇论文(平均影响因子12)，他引11000 余次，授权专利10余项。主持国自然科学基金优秀青年基金/重大研究计划培育项目、科技部重点研发子课题等20余项国家/省部级项目，部分研究成果获得重庆市自然科学奖一等奖（第三），重庆大学教学成果奖一等奖和二等奖。
人才称号
国家自然科学基金委优秀青年基金项目、重庆市杰出青年基金项目和重庆市青年拔尖人才支持计划
中国细胞生物学会理事
中国生物物理学会微量元素分会常务委员/副秘书长
中国生物材料学会纳米生物材料分会/智能仿生材料分会/复合材料分会委员
重庆市细胞生物学学会副理事长
重庆市抗癌协会副主任委员
国家骨科与运动康复临床医学研究中心学术委员会青年委员
代表性论文
1.Siyu Guo#, Xueting Ren#, Xijiao Ren#, Jinming He, Huocheng Yang, Wei Zhou, Menghuan Li, Lulu Wang*, Yan Hu*, Zhong Luo*. Supramolecular DNA Di-Tetrahedral Neoadjuvants Dynamically Prime Melanoma Microenvironment for Enhancing Radio-Immunotherapy Responses. Advanced Functional Materials 2026, 36: e24385.
2. Huocheng Yang, Yingqi Liu, Menghuan Li, Xiaodong Zhang, Yanli Zhao*, Zhong Luo*. Photo-Controlled MUC1 Ablation via Steric Locking of Turn-On Reactors Enhances Pyroptosis-Immunotherapy of Triple Negative Breast Cancer. Advanced Materials 2025, 38(7):e04460.
3.Yinglong Wu, Lihe Sun, Xiaodong Zhang, Wenbin Zhong, Xiaokai Chen, Shihuai Wang, Yun Chen, Dongdong Wang, Ting He, Hongzhong Chen, Jingjing Guo, Fang Zeng, Menghuan Li, Zhong Luo*, Shuizhu Wu*, Yanli Zhao*. Unnatural Triggers Converted From Tetrazine-Attached Sialic Acid for Activation of Optoacoustic Imaging-Guided Cancer Theranostics. Angew Chem Int Ed 2025, 64, 26: e202503850.
4. Wenkai Wang#, Zhuo Cheng#, Miao Yu, Ke Liu, Hongli Duan, Yang Zhang, Xinle Huang, Menghuan Li, Changqing Li, Yan Hu*, Zhong Luo*, Minghan Liu*. Injectable ECM-mimetic dynamic hydrogels abolish ferroptosis-induced post-discectomy herniation through in-situ delivery of nucleus pulposus progenitor cell-derived exosomes. Nature Communications 2025, 16:3131.
5. Haibing Wang, Yilong Dong, Jiayi Zhang, Haifeng Zhang, Junnian Chen, Siya Wang, Huocheng Yang, Menghuan Li, Yan Hu*, and Zhong Luo*. Living microecological microneedle patches enable proregenerative microenvironmental remodeling for promoting infected diabetic wound healing. ACS Nano 2025, 19, 23:21739-21756.
6. Haifeng Zhang#, Wei Zhou#, Haibing Wang, Jiayi Zhang, Huocheng Yang, Junnian Chen, Siya Wang, Weikang Zhao*, Menghuan Li*, Zhong Luo*. Hydrogel-based bioactive synthetic skin enables integrative stimulation of regenerative gas signaling and elimination of interfacial bacteria to promote burn wound healing. ACS Nano 2025, 19, 15:15002-15017.
7. Xijiao Ren#, Rui Xue#, Yan Luo#, Shuang Wang, Xinyue Ge, Xuemei Yao, Liqi Li, Junxia Min, Menghuan Li*, Zhong Luo*, Fudi Wang*. Programmable melanoma-targeted radio-immunotherapy via fusogenic liposomes functionalized with multivariate-gated aptamer assemblies. Nature Communications 2024, 15(1): 49482-9.
8. Xuan Wang#, Qiqi Zhang, Jinming He, Yingqi Liu*, Menghuan Li*, Zhong Luo*, Youbo Zhao#, Xin Li. Liposomal STAT3-degrading PROTAC prodrugs promote anti-hepatocellular carcinoma immunity via chemically reprogramming cancer stem cells. Nano Letters 2024, 24(16): 4858-4868.
9. Xijiao Ren, Zhuo Cheng, Jinming He, Xuemei Yao, Yingqi Liu, Kaiyong Cai, Menghuan Li*, Yan Hu*, Zhong Luo*. Inhibition of glycolysis-driven immunosuppression with a nano-assembly enhances response to immune checkpoint blockade therapy in triple negative breast cancer. Nature Communications 2023, 14: 7021.
10. Yingqi Liu, Xuemei Yao, Youbo Zhao, De Fang, Lei Shi, Li Yang, Guanbin Song, Kaiyong Cai, Liqi Li, Qin Deng, Menghuan Li*, Zhong Luo*. Mechanotransduction in response to ecm stiffening impairs cGAS immune signaling in tumor cells. Cell Reports 2023, 42: 113213.
11. Yanan Li#, Menghuan Li#, Li Liu, Chencheng Xue, Yang Fei, Xuan Wang, Yuchen Zhang, Kaiyong Cai, Yanli Zhao*, Zhong Luo*. Cell-specific metabolic reprogramming of tumors for bioactivatable ferroptosis therapy. ACS Nano 2022, 16: 3965-3984.
12. Youbo Zhao, Menghuan Li, Xuemei Yao, Yang Fei, Zhenghong Lin, Zhengguo Li, Kaiyong Cai, Yanli Zhao, Zhong Luo*. HCAR1/MCT1 regulates tumor ferroptosis through the lactate-mediated AMPK-SCD1 activity and its therapeutic implications. Cell Reports 2020, 33: 108487.
13. Chencheng Xue#, Menghuan Li#, Yang Zhao#, Jun Zhou, Yan Hu, Kaiyong Cai, Yanli Zhao, Shuhong Yu*, Zhong Luo*. Tumor microenvironment-activatable Fe-doxorubicin preloaded amorphous CaCO3 nanoformulation triggers ferroptosis in target tumor cells. Science Advances 2020, 6: eaax1346.
14.Jun Zhou, Menghuan Li, Yanhua Hou, Zhong Luo*, Qiufang Chen, Hexu Cao, Runlan Huo, Chencheng Xue, Linawati Sutrisno, Lan Hao, Yang Cao, Haitao Ran, Lu Lu, Ke Li, Kaiyong Cai*. Engineering of a nanosized biocatalyst for combined tumor starvation and low-temperature photothermal therapy. ACS Nano 2018, 12: 2858-2872.
15. Zhong Luo, Kaiyong Cai*, Yan Hu, Jinghua Li, Xingwei Ding, Beilu Zhang, Dawei Xu, Weihu Yang, Peng Liu. Redox-responsive molecular nanoreservoirs for controlled intracellular anticancer drug delivery based on magnetic nanoparticles. Advanced Materials 2012, 24:431-435.
16. Zhong Luo, Kaiyong Cai*, Yan Hu, Li Zhao, Peng Liu, Lin Duan, and Weihu Yang. Mesoporous silica nanoparticles end-capped with collagen: redox-responsive nanoreservoirs for targeted drug delivery. Angewandte Chemie International Edition 2011, 50: 640-643.
