Ze Zhang, Ph.D.

Professor of Evolutionary Genetics
Laboratory of Evolutionary and Functional Genomics
School of Life Sciences
Chongqing University
No.55 Daxuecheng South Rd.,Shapingba District
Chongqing University Huxi Campus
Chongqing 401331
Tel: +86-23-65678449; E-mail:zezhang@cqu.edu.cn

Research Interests

1. The Genetics of Silkworm Domestication
The domesticated silkworm (Bombyx mori) was domesticated from the wild silkworm (Bombyx mandarina) about 5,000-10,000 years ago. In the Silk Road era about 2,000 years ago, the domesticated silkworm played a crucial role in globalization. It is generally thought that the domesticated silkworm initially originated from China and then spread to Europe, Japan, and other countries. Currently, the wild silkworm exists in fields. This provides a good opportunity for studying the genetics of silkworm domestication by comparing the genomes of the domesticated and wild silkworms. Long term artificial selection of domestication and breeding has made the domesticated silkworm quite different from the wild silkworm in both morphological and behavioral traits. What is the genetical basis of differences in morphology and behavior between the domesticated and wild silkworms? Which changes of genes made the domesticated silkworm from the wild silkworm? Did the artificial and natural selections leave the signatures in the corresponding genomes? If so, are they different from each other? Now, we are trying to answer the above questions at molecular level.

2. The Annoation and Functional Characterization of Transposable Elements (TEs) in the Silkworm
Genome-wide annotation of the silkworm (Bombyx mori) genome revealed that ~40% of the genome is composed of TEs. This proportion is the largest one in the insect genomes sequenced to date except for mosquito Aedes aegypti with 47% of the genome being TEs. Now, we are doing (1) comprehensive annotation of TEs in silkworm, (2) the study of horizontal transfer of TEs in insects, (3) the functional characterization of TEs in silkworm. In addition, we constructed the Database of the silkworm TEs-BmTEdb (http://gene.cqu.edu.cn/BmTEdb/).


2008.1- Professor, School of Life Sciences, Chongqing University, China
2006.2-2007.12 Professor, The Institute of Sericulture and Systems Biology, Southwest University, China
2004.2-2006.1 Research Fellow, School of Biosciences, The University of Birmingham, UK
2002.2-2004.1 JST Research Fellow, in Prof. Hirohisa Kishino lab, work on evolution of duplicated genes, The University of Tokyo, Japan
2000.10-2002.1 Research Scientist, Southwest Agricultural University, China
1998.10-2000.9 Postdoc with Prof. Tsuneyuki Yamazaki, work on the evolution of amylase multigene family in Drosophila, Kyushu University, Japan
1997.1-1998.9 Research Scientist, Southwest Agricultural University, China
1996.12 PhD, Thesis: "The Genetic Analysis of Amount of Laid Eggs and Evaluation for Mating Designs and Variety Stability in Silkworm (Bombyx mori L.)." Southwest Agricultural University, China
1992.9-1996.12 PhD studies on Quantitative and Population Genetics in Silkworm, Southwest Agricultural University, China
1986.8-1992.8 Lecturer, Department of Agronomy, Southwest Agricultural University, China
1983.9-1986.7 Diplom (M.Sc.) in Quantitative Genetics and Crop Breeding, Southwest Agricultural University, China
1979.9-1983.7 Diplom (B.Sc.) in Agronomy, Southwest Agricultural College, China


Last modified: 10 August 2016